Fig. 1
From: The A’-helix of CYP11A1 remodels mitochondrial cristae
CYP11A1 remodels mitochondria cristae into tubulovesicular shape. A Western blot showing CYP11A1 expression in C1 and C4 cells when induced with doxycycline (+ doxy). B The amount of P5 production is increased after induction of CYP11A1 with doxycycline in C1 and C4 cells. C TEM images of lamellar cristae in COS1 cells and tubulovesicular cristae in stable cell clone C4 after doxycycline induction of CYP11A1 (C4 +). D More cells contain tubulovesicular cristae in their mitochondria after induction with doxycycline (doxy) observed under TEM. Unpaired t-test was used, and data shown are mean with standard deviation