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Table 2 Distribution of phylogenetic groups and virulence factor (VF) genes in relation to papG alleles among E. coli isolates from reproductive-age women with pyelonephritis

From: Distribution of papG alleles among uropathogenic Escherichia coli from reproductive age women

Trait

Number (%) of isolates

P valued

Phylogenetic group or VF genea

papG negb

(n = 73)

papG posc

(n = 221)

papGII + 

(n = 200)

papGIII + 

(n = 12)

papG neg vs. papG pos

papGII vs. papGIII

A

1 (1)

7 (3)

0 (0)

1 (8)

NSe

0.056

B1

2 (3)

4 (2)

0 (0)

1 (8)

NS

0.056

B2

47 (64)

189 (86)

196 (98)

7 (58)

0.005

 < 0.001

C

1 (1)

2 (1)

1 (1)

1 (1)

NS

NS

D

18 (24)

15 (7)

4 (2)

3 (25)

 < 0.001

0.004

E

1 (1)

2 (1)

1 (1)

1 (1)

NS

NS

F

2 (3)

4 (2)

2 (1)

2 (1)

NS

NS

Clade 1

0 (0)

0 (0)

0 (0)

0 (0)

NS

NS

afa

18 (25)

13 (6)

9 (5)

3 (25)

 < 0.001

0.023

bmaE

0 (0)

4 (2)

0 (0)

0 (0)

NS

NS

cnf1

19 (26)

113 (51)

104 (52)

4 (33)

 < 0.001

NS

fimH

67 (92)

221 (100)

200 (100)

10 (83)

 < 0.001

0.003

focG

34 (46)

117 (53)

107 (54)

4 (33)

 < 0.001

NS

fyuA

60 (82)

144 (65)

132 (66)

6 (50)

0.006

NS

gafD

0 (0)

3 (1)

0 (0)

0 (0)

NS

NS

hlyA

38 (52)

144 (65)

137 (69)

5 (42)

0.052

NS

iutA

48 (66)

190 (86)

182 (91)

8 (67)

 < 0.001

0.025

kpsII

42 (58)

168 (76)

144 (72)

6 (50)

0.004

NS

kpsIII

7 (10)

18 (8)

18 (9)

0 (0)

NS

NS

papAH

42 (58)

199 (90)

189 (95)

10 (83)

 < 0.001

NS

papC

45 (62)

212 (96)

200 (100)

9 (75)

 < 0.001

 < 0.001

papEF

44 (60)

212 (96)

196 (98)

10 (83)

 < 0.001

0.039

sfaS

13 (18)

73 (33)

70 (35)

3 (25)

0.017

NS

traT

51 (70)

151 (76)

140 (70)

10 (83)

NS

NS

ompT

46 (63)

146 (73)

136 (68)

8 (67)

NS

NS

usp

50 (68)

143 (72)

132 (66)

9 (75)

NS

NS

f,gVF score (Median, range)

5 (1–9)

8 (3–15)

10 (3–15)

7 (2–10)

0.012

0.015

  1. aThe 22 virulence factors (VFs) analyzed were; papA, P fimbriae structural subunit; papC, P fimbriae assembly; papEF, fimbriae tip pilins; papG, P fimbriae adhesin (and alleles I, II and III); sfaS, S fimbriae; focG, F1C fimbriae; afa/draBC, Afimbrial adhesin (Dr-binding adhesin); fimH, type 1 fimbriae; hlyA, hemolysin; cnf1, cytotoxic necrotizing factor type1; fyuA, ferric yersiniabactin receptor; iutA, aerobactin receptor; iroN, catecholate siderophore receptor; kpsMTII group 2 capsule (with K1 and K2 variants); kpsMTIII, group 3 capsule; traT, serum-resistance associated; ompT, outer membrane protein T (protease); bmaE, M fimbriae; gafD, (G) fimbriae
  2. bpapG neg, papG gene negative (for all alleles)
  3. cpapG pos, papG gene positive (for any allele)
  4. dP values (by Fisher’s exact test) are shown where P < 0.05
  5. eNS, not statistically significant, P > 0.05
  6. fVF score, sum of all VF genes tested, with pap operon genes counted as a unit
  7. gP values by Mann–Whitney test are shown where P < 0.05