Table 2 TRIM expression and related clinical characteristics

TRIM3

Low

129

OS

0.562

(0.356–0.888)

0.014

Tumor size, histological grade, AFP, TNM stage

[19]

TRIM7

High

84

OS

–

0.0044

Tumor size, pTNM stage, serum HBV DNA copy number, and AFP

[43]

Low

80

[14]

TRIM11

High

117

OS

2.98

(1.19–4.72)

 < 0.01

AFP, pathological grade

[28]

DFS

2.34

(0.92–3.26)

0.031

TRIM14

High

166

OS

1.657

(1.031–2.687)

0.018

ALT, CRP, tumor size, tumor number, vascular invasion, BCLC stages, and TNM stages

[29]

RFS

2.297

(1.184–2.312)

0.007

TRIM16

Low

61

–

–

–

[20]

PML

High

40

OS

0.038

Age, HBsAg positive

[30]

Cumulative relapse rate

0.01

TRIM25

High

25

–

–

–

[32]

TRIM26

Low

242

OS

–

0.0265

AFP, American Joint Committee on Cancer (AJCC) T stage, Cancer Liver Italian Program (CLIP) stage

[21]

RFS

0.0308

TRIM28

High

116

OS

2.151

(1.032–4.486)

0.041

AFP, tumor size, tumor stage

[33]

TRIM29

High

90

OS

–

0.011

[45]

LOW

20

–

–

–

Vascular invasion, Tumor differentiation

[44]

TRIM31

High

108

 < 0.001

Tumor volumes, TNM stages, Edmenson grade

[34]

TRIM32

High

116

OS

0.523

(0.286–0.958)

 < 0.01

Histological grade, tumor size, HBsAg positive

[35]

TRIM33

Low

204

OS

1.898

(1.101–3.268)

0.021

Tumor encapsulation, vascular invasion, differentiation, TNM stage, and BCLC stage

[22]

Recurrence

1.751

(1.155–2.653)

0.008

TRIM35

Low

688

OS

0.586

(0.376–0.913)

0.018

[23]

Time to recurrence

0.643

(0.435–0.950)

0.027

TRIM37

High

90

OS

–

0.029

Tumor size, tumor stage

[36]

High

53

DFS

0.012

[37]

TRIM44

High

106

OS

3.442

(1.318–8.989)

0.012

Tumor size, vascular invasion, intrahepatic metastasis, distant metastasis

[38]

TRIM50

Low

79

TNM stages, BCLC stages, and metastasis

[24]

TRIM52

High

87

TNM stages, tumor number

[39]

TRIM55

Low

100

OS

0.425

(0.193–0.934)

0.033

vascular invasion, TNM stages

[25]

TRIM56

Low

41

OS/RFS

–

–

T stage

[26]

TRIM58

Low

43

[27]

TRIM59

High

103

OS

 < 0.01

Tumor size

[40]

TRIM66

High

88

TNM stages

[41]

TRIM71

High

106

OS

0.008

AFP, tumor grade, tumor stage, early recurrence

[42]