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Table 4 Distribution of VF genes in relation to fluoroquinolone resistance status among E. coli ST131 isolates from women

From: Possible step-up in prevalence for Escherichia coli ST131 from fecal to clinical isolates: inferred virulence potential comparative studies within phylogenetic group B2

Trait

Number (%) of isolates with trait by source and ST131 status

P value by isolate source (vs. ST131)a

Fecal (n = 23)

Clinical (n = 131)

FQ-R-ST131 (n = 7)

FQ-S-ST131 (n = 16)

FQ-R-ST131 (n = 65)

FQ-S-ST131 (n = 59)

Fecal

Clinicalb

ESBL

3 (42)

1 (6)

50 (77)

26 (44)

 < 0.001

< 0.001

O25b

7 (100)

16 (100)

55 (85)

50 (94)

NS

NS

O16

0 (0)

0 (0)

10 (15)

3 (5)

NS

< 0.001

VF genesc

afa/draBC

1 (14)

3 (19)

6 (9)

14 (24)

NS

< 0.001

bmaE

0 (0)

0 (0)

1 (2)

0 (0)

NS

NS

sfaS

1 (14)

3 (19)

7 (11)

14 (24)

NS

< 0.001

fimH

7 (100)

16 (100)

65 (100)

59 (100)

NS

NS

focG

2 (29)

7 (44)

44 (68)

17 (29)

0.041

< 0.001

papGI

0 (0)

0 (0)

0 (0)

1 (2)

NS

NS

papGII

1 (14)

4 (25)

25 (38)

10 (17)

0.031

< 0.001

papGIII

1 (14)

3 (19)

20 (31)

7 (12)

0.041

< 0.001

papAH

2 (29)

7 (44)

46 (71)

19 (32)

0.032

< 0.001

papC

2 (29)

5 (31)

44 (68)

21 (36)

NS

< 0.001

papEF

2 (29)

4 (25)

44 (68)

19 (32)

NS

< 0.001

gafD

0 (0)

0 (0)

1 (2)

0 (0)

NS

NS

cnf1

1 (14)

3 (19)

44 (68)

18 (31)

NS

< 0.001

hlyA

1 (14)

3 (19)

47 (72)

187(29)

NS

< 0.001

iutA

7 (100)

16 (100)

65 (100)

59 (100)

NS

NS

fyuA

5 (71)

11 (69)

65 (100)

47 (80)

NS

0.01

iroN

3 (43)

6 (38)

57 (88)

25 (42)

NS

< 0.001

kpsMTII

1 (14)

5 (31)

33 (51)

59 (100)

0.028

NS

KpsMTIII

0 (0)

0 (0)

0 (0)

0 (0)

NS

NS

traT

7 (100)

16 (100)

65 (100)

59 (100)

NS

NS

ompT

7 (100)

16 (100)

65 (100)

59 (100)

NS

NS

usp

7 (100)

16 (100)

65 (100)

59 (100)

NS

NS

  1. ESBL, extended spectrum β-lactamase; FQ-R, fluoroquinolone resistant; FQ-S, fluoroquinolone susceptible
  2. aP values are shown where P < 0.05, calculated by Fisher’s exact test. NS, non-significant
  3. bClinical, cystitis and pyelonephritis isolates
  4. cThe 22 virulence factors analyzed were; papA, P fimbriae structural subunit; papC, P fimbriae assembly; papEF, fimbriae tip pilins; papG, P fimbriae adhesin (and alleles I, II and III); sfaS, S fimbriae; focG, F1C fimbriae; afa/draBC, Afimbrial adhesin (Dr-binding adhesin); fimH, type 1 fimbriae; hlyA, hemolysin; cnf1, cytotoxic necrotizing factor type1; fyuA, ferric yersiniabactin receptor; iutA, aerobactin receptor; iroN, catecholate siderophore receptor; kpsMTII group 2 capsule (with K1 and K2 variants); kpsMTIII, group 3 capsule; traT, serum-resistance associated; ompT, outer membrane protein T (protease); bmaE, M fimbriae; gafD, (G) fimbriae