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Table 5 Distribution of VF genes in relation to fluoroquinolone (FQ) resistance status among E. coli ST131 isolates from men

From: Possible step-up in prevalence for Escherichia coli ST131 from fecal to clinical isolates: inferred virulence potential comparative studies within phylogenetic group B2

Trait

Number (%) of isolates with trait by source and ST131 status

P value by isolate source (vs. ST131)a

Fecal (n = 8)

Clinical (n = 49)

FQ-R-ST131 (n = 5)

FQ-S-ST131 (n = 3)

FQ-R-ST131 (n = 27)

FQ-S-ST131 (n = 22)

Fecal

Clinicalb

ESBL

2 (40)

0 (0)

18 (67)

10 (45)

 < 0.001

 < 0.001

O25b

5 (100)

3 (100)

22 (82)

21 (96)

NS

NS

O16

0 (0)

0 (0)

5 (19)

1 (4)

NS

< 0.001

VF genesc

afa/draBC

1 (20)

0 (0)

1 (4)

4 (18)

NS

< 0.001

bmaE

0 (0)

0 (0)

1 (4)

0 (0)

NS

NS

sfaS

1 (20)

0 (0)

2 (7)

5 (23)

NS

< 0.001

fimH

5 (100)

3 (100)

27 (100)

22 (100)

NS

NS

focG

1 (20)

1 (33)

18 (67)

6 (27)

0.031

< 0.001

papGI

0 (0)

0 (0)

0 (0)

0 (0)

NS

NS

papGII

1 (20)

1 (33)

8 (30)

3 (14)

0.031

< 0.001

papGIII

1 (20)

1 (33)

8 (30)

4 (18)

0.039

< 0.001

papAH

1 (20)

1 (33)

16 (59)

6 (27)

0.030

< 0.001

papC

1 (20)

1 (33)

15 (56)

7 (32)

NS

< 0.001

papEF

1 (20)

1 (33)

16 (59)

7 (32)

NS

< 0.001

gafD

0 (0)

0 (0)

1 (4)

0 (0)

NS

NS

cnf1

1 (20)

1 (33)

17 (63)

8 (36)

NS

< 0.001

hlyA

1 (20)

1 (33)

18 (67)

6 (27)

NS

< 0.001

iutA

5 (100)

3 (100)

27 (100)

22 (100)

NS

NS

fyuA

3 (60)

2 (67)

27 (100)

16 (73)

NS

0.01

iroN

2 (40)

1 (33)

22 (81)

9 (41)

NS

< 0.001

kpsMTII

1 (20)

1 (33)

13 (48)

22 (100)

0.027

NS

KpsMTIII

0 (0)

0 (0)

0 (0)

0 (0)

NS

NS

traT

5 (100)

3 (100)

27 (100)

22 (100)

NS

NS

ompT

5 (100)

3 (100)

27 (100)

22 (100)

NS

NS

usp

5 (100)

3 (100)

27 (100)

22 (100)

NS

NS

  1. ESBL, extended spectrum β-lactamase; FQ-R, fluoroquinolone resistant; FQ-S, fluoroquinolone susceptible
  2. aP values are shown where P < 0.05, calculated by Fisher’s exact test. NS, non-significant
  3. bClinical, cystitis and pyelonephritis isolates
  4. cThe 22 virulence factors analyzed were; papA, P fimbriae structural subunit; papC, P fimbriae assembly; papEF, fimbriae tip pilins; papG, P fimbriae adhesin (and alleles I, II and III); sfaS, S fimbriae; focG, F1C fimbriae; afa/draBC, Afimbrial adhesin (Dr-binding adhesin); fimH, type 1 fimbriae; hlyA, hemolysin; cnf1, cytotoxic necrotizing factor type1; fyuA, ferric yersiniabactin receptor; iutA, aerobactin receptor; iroN, catecholate siderophore receptor; kpsMTII group 2 capsule (with K1 and K2 variants); kpsMTIII, group 3 capsule; traT, serum-resistance associated; ompT, outer membrane protein T (protease); bmaE, M fimbriae; gafD, (G) fimbriae