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Table 7 Distribution of VF genes in relation to fluoroquinolone resistance status and ESBL among E. coli ST131 clinical isolates from women, men and children

From: Possible step-up in prevalence for Escherichia coli ST131 from fecal to clinical isolates: inferred virulence potential comparative studies within phylogenetic group B2

VF genesb

Number (%) of isolates with trait by source and ST131 status

P value by isolate source (ESBL vs. non-ESBL)a

FQ-R (n = 142)

FQ-S (n = 131

ESBL (n = 105)

Non-ESBL (n = 37)

ESBL (n = 53)

Non-ESBL (n = 78)

FQ-R

FQ-S

afa/draBC

13 (12)

14 (38)

10 (19)

31 (40)

 < 0.001

 < 0.001

bmaE

2 (2)

0 (0)

0 (0)

0 (0)

NS

ns

sfaS

17 (16)

13 (36)

10 (19)

31 (40)

 < 0.001

0.004

fimH

105 (100)

37 (100)

53 (100)

78 (100)

NS

NS

focG

85 (81)

22 (59)

31 (58)

33 (42)

0.003

0.023

papGI

2 (2)

0 (0)

0 (0)

0 (0)

NS

NS

papGII

70 (67)

22 (59)

15 (29)

13 (16)

0.032

< 0.001

papGIII

60 (57)

15 (41)

9 (17)

16 (20)

0.04

NS

papAH

76 (72)

12 (32)

17 (32)

26 (33)

< 0.001

NS

papC

72 (69)

19 (50)

19 (35)

30 (38)

0.003

NS

papEF

82 (78)

22 (59)

15 (29)

31 (40)

< 0.001

< 0.001

gafD

2 (2)

0 (0)

0 (0)

0 (0)

NS

NS

cnf1

70 (67)

20 (55)

28 (52)

30 (38)

0.002

< 0.001

hlyA

76 (72)

15 (41)

22 (42)

23 (29)

< 0.001

< 0.001

iutA

105 (100)

37 (100)

53 (100)

78 (100)

NS

NS

fyuA

105 (100)

37 (100)

53 (100)

78 (100)

NS

NS

iroN

18 (17)

7 (18)

7 (13)

3 (4)

NS

0.031

kpsMTII

105 (100)

37 (100)

53 (100)

78 (100)

NS

NS

kpsMTIII

2 (2)

0 (0)

0 (0)

0 (0)

NS

NS

traT

105 (100)

22 (100)

53 (100)

78 (100)

NS

NS

ompT

105 (100)

22 (100)

53 (100)

78 (100)

NS

NS

usp

105 (100)

22 (100)

53 (100)

78 (100)

NS

NS

  1. ESBL, extended spectrum β-lactamase; FQ-R, fluoroquinolone resistant; FQ-S, fluoroquinolone susceptible
  2. aP values are shown where P < 0.05, calculated by Fisher’s exact test. NS, non-significant
  3. bThe 22 virulence factors analyzed were; papA, P fimbriae structural subunit; papC, P fimbriae assembly; papEF, fimbriae tip pilins; papG, P fimbriae adhesin (and alleles I, II and III); sfaS, S fimbriae; focG, F1C fimbriae; afa/draBC, Afimbrial adhesin (Dr-binding adhesin); fimH, type 1 fimbriae; hlyA, hemolysin; cnf1, cytotoxic necrotizing factor type1; fyuA, ferric yersiniabactin receptor; iutA, aerobactin receptor; iroN, catecholate siderophore receptor; kpsMTII group 2 capsule (with K1 and K2 variants); kpsMTIII, group 3 capsule; traT, serum-resistance associated; ompT, outer membrane protein T (protease); bmaE, M fimbriae; gafD, (G) fimbriae