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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review

Fig. 3

Growth factors in stem cells secretions and their contribution to hair regeneration. A Canonical Wnt signaling pathway induction and inactivation of noncanonical Wnt signaling pathway by SDF1, MMP3, and biglycan respectively. The latter proteins are secreted by DPCs due to their activation by GFs. B Role of LTBP1 secreted by DPC in hair regeneration. Inactivation of Bmp signaling pathway. Bind with TGF β and activate Smad 2/3 and TGF β pathways

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