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Fig. 4 | Journal of Biomedical Science

Fig. 4

From: Stem cell secretome as a mechanism for restoring hair loss due to stress, particularly alopecia areata: narrative review

Fig. 4

Role of cytokines of stem cell secretions in hair regeneration. A VEGF contributes to more perifollicular vascularization in the anagen phase and less in perifollicular vascularization in the telogen phase thus restoring hair. B, C IGFBP1 and hepatocyte growth factor induce hair regeneration through increasing beta-catenin expression. D Role of PDGF in hair regeneration by elevating Shh and LEF1

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