Table 4 Differentially expressed genes (> 1.0 log2FC and FDR ≤ 0.05) at 1 h induced by polymyxin B monotherapy
Locus tag/gene name | Product description | Expression ratio (log2) | Adjusted p-value |
|---|---|---|---|
PA2018 (mexY) | RND multidrug efflux transporter | 2.82 | 5.17E−08 |
PA2019 (mexX) | RND multidrug efflux membrane fusion protein | 2.89 | 5.27E−06 |
PA4611 (pagL) | Lipid A 3-O-deacylase | 1.02 | 0.00283 |
PA2354 | Transcriptional regulator | 2.96 | 0.00011 |
PA2356 (msuD) | Methanesulfonate sulfonatase | 4.24 | 0.00088 |
PA2357 (msuE) | NADH-dependent FMN reductase | 5.55 | 0.00062 |
PA4209 (phzM) | Phenazine specific methyltransferase | 1.34 | 0.00666 |
PA4210 (phzA1) | Phenazine biosynthesis protein | 1.13 | 0.04192 |
PA1559 | Hypothetical protein | 3.06 | 0.00015 |
PA1560 | Hypothetical protein | 2.55 | 0.00042 |
PA4774 | Hypothetical protein | 3.54 | 0.00066 |
PA4775 | Hypothetical protein | 1.44 | 0.00721 |
PA4773 | Hypothetical protein | 3.62 | 0.00014 |