Fig. 6

Impairment of MAC mediated bacterial killing by CHB patient sera. a C9 deposition on E. coli treated with CHB patient sera in comparison to HC sera. b CFU count of E. coli on agar plates incubated at 37 °C for 16 h after treatment with HC sera, C9 deficient CHB sera or heat inactivated HC sera. Determination of c Bacterial-DNA by Real-time PCR and d endotoxin concentration by ELISA in the sera of IT, CHB (including both EP- and EN-CHB), IC and HC. Correlation analysis between serum C9 level and e bacterial DNA and f endotoxin titre in study subjects. Paired t test was performed in a. One-way ANOVA followed by Tukey’s multiple comparison were used in (b)-(d). *p < 0.05, **p < 0.005, ***p < 0.0001