Fig. 3
From: Spatial multi-omics analyses of the tumor immune microenvironment
CODEX analysis of a mouse B cell lymphoma model reveals immune exhaustion in tumor core. A DAPI staining from the CODEX image stack, showing a clear tumor compartment. B Composite image of two markers extracted from the same CODEX image stack showing that the exhausted marker, PD-1 (red), co-localizes with CD8+ TILs (green) residing within the tumor area. C Cell–cell interactions based on CODEX neighborhood analysis; strong to weak correlations are light green to dark blue