Fig. 4

Proliferation and apoptosis signaling in ectopic lesions with oleuropein treatment. a Inhibition of proliferation in ectopic lesions by oleuropein. Oleuropein reduced the expression of KI-67 in epithelial, but not stromal, cells in mouse ectopic lesions. b Activation of apoptosis in ectopic lesions by oleuropein. Oleuropein increased the expression of the cleaved form of caspase 3 in both epithelial and stromal cells in mouse ectopic lesions. **, P < 0.01; NS nonspecific. Scale bar is 50 μm