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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis

Fig. 6

Effect of oleuropein on the pregnancy rate of mice with endometriosis and decidualization of human endometriotic stromal cells. a The pregnancy rate of mice with endometriosis treated with vehicle or oleuropein (25 mg/kg). Wild-type mice without endometriosis were employed as the endometriosis control (No endometriosis). b The litter size of mice with endometriosis treated with vehicle or oleuropein and the endometriosis control. c, d The expression levels of PRL (c) and IGFBP1 (d) in normal human endometrial stromal cells (Normal) and endometriotic stromal cells from ectopic lesions of endometriosis patients (Endo) on the 3rd day after decidualization cocktail (EPC) treatment. e, f The expression levels of PRL (e) and IGFBP1 (f) in normal human endometrial stromal cells (Normal) on the 3rd day after decidualization cocktail treatment in the presence of different doses of oleuropein. g, h The expression levels of PRL (g) and IGFBP1 (h) in human endometriotic stromal cells (Endo) on the 3rd day after decidualization cocktail treatment in the presence of different doses of oleuropein. *, p < 0.05; **, P < 0.01; ***, p < 0.001; NS nonspecific

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