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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Modulation of histone H3K4 dimethylation by spermidine ameliorates motor neuron survival and neuropathology in a mouse model of ALS

Fig. 6

SD administration improves rotarod and gait performance of ALS (G93A) mice. A SD was administered to the mice from 70 to 120 days of age, then rotarod and wheel tests were performed. B SD administration significantly improved rotarod performance of ALS (G93A) mice (n = 3) compared to vehicle (saline)-treated ALS mice (n = 4). C Footprint analysis from the accelerating wheel test. D Gait analysis showed that SD administration improved the increase of stride width in ALS mice. Significantly different at *p < 0.05

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