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Fig. 2 | Journal of Biomedical Science

Fig. 2

From: Reduced virulence in tigecycline-resistant Klebsiella pneumoniae caused by overexpression of ompR and down-regulation of ompK35

Fig. 2

Expression levels of ompR and ompK35. A The expression levels of ompK35 and ompR in tigecycline-susceptible, wild-type K. pneumoniae strains (109 and 200) and tigecycline-resistant mutants derived from wild-type strains (109-IR and 200-IR). B ompR expression levels with different tigecycline concentrations in tigecycline-resistant K. pneumoniae mutants (109-IR and 200-IR). C ompR expression levels in ompR-overexpressed mutants from wild-type strains (109/ompR and 200/ompR), ompR-deleted mutants from tigecycline-resistant strains (109-IRΔompR and 200-IR ΔompR), and ompR-complemented mutants (109-IRΔompR-C and 200-IR ΔompR-C). D ompK35 expression levels in ompR-overexpressed mutants from wild-type strains (109/ompR and 200/ompR), ompR-deleted mutants from tigecycline-resistant strains (109-IRΔompR and 200-IR ΔompR), and ompR-complemented mutants (109-IRΔompR-C and 200-IR ΔompR-C). *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001

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Journal of Biomedical Science

ISSN: 1423-0127