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Fig. 3 | Journal of Biomedical Science

Fig. 3

From: A transcriptomic pan-cancer signature for survival prognostication and prediction of immunotherapy response based on endothelial senescence

Fig. 3

Pan-cancer analysis of EC.SENESCENCE.SIG. A Enrichment analysis of several tumor-promoting pathways between tumor tissues with high and low EC.SENESCENCE.SIG scores across 33 cancer types in TCGA cohorts, NES normalized enrichment score in the GSEA algorithm, FDR false discovery rates. B Summary of the relationship between EC.SENESCENCE.SIG scores and OS/PFS of patients across 33 cancer types in TCGA pan-cancer cohorts. Expression of genes associated with poorer prognosis (yellow) or better prognosis (blue) are shown. C The correlation of EC.SENESCENCE.SIG scores and immune infiltration (Cibersort) across 33 cancer types in TCGA cohorts is shown, blue dots represent a negative correlation, red dots a positive correlation

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