Journal of Biomedical Science is supported by the National Science and Technology Council (NSTC), Taiwan.
Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteins
Mitoxantrone is a potent antitumor drug, widely used in the treatment of various cancers. In the present study, we have investigated and compared the affinity of anticancer drug, mitoxantrone, to EDTA-soluble ...