Figure 1From: Studies on the binding affinity of anticancer drug mitoxantrone to chromatin, DNA and histone proteinsTurbidity measurements at 400 nm of the interaction of various concentrations of mitoxantrone with SE-chromatin (diamond), SE-DNA (triangle) and thymus DNA (square). The reaction was carried out in 10 mM Tris-HCl (pH 7.5) and incubation time was 45 min at 23°C. Results are average of 3 individual experiments.Back to article page