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Table 2 Acetylcholine esterase activity in the corpus striatum of Control, Diabetic and D+I group rats

From: Enhanced muscarinic M1 receptor gene expression in the corpus striatum of streptozotocin-induced diabetic rats

Animal status

Vmax

(μmoles/min/mg protein)

Km (μM)

Control

2420.0 ± 11.5

51.0 ± 0.5

Diabetic

1631.3 ± 16.1***

51.3 ± 0.8

Diabetic + Insulin treated (D+I)

2647.0 ± 26.5ψψψ

51.0 ± 0.5

  1. Values are mean ± S.E.M of 4–6 separate experiments. Each group consist of 6–8 rats
  2. *** P < 0.001 when compared to control, ψψψ P < 0.001 when compared to diabetic group