Table 6 Binding parameters of [3H]QNB against pirenzepine in the corpus striatum of Control, Diabetic and Diabetic+Insulin treated group rats
Experimental Group | Best-fit model | Log (EC50) | Ki | Hill slope |
|---|---|---|---|---|
Control | One-site | -7.107 | 2.23 × 10-8 | 0.7224 |
Diabetic | One-site | -6.459 | 9.92 × 10-8 | 0.7444 |
Insulin treated diabetic | One-site | -7.322 | 4.76 × 10-8 | 0.6826 |