Table 3 The Effects of Commonly Used Antioxidants or Inhibitors of ROS-Generating Enzymes on TNFα-, Glutamate- and Oligomycin-Induced Cytotoxicity.
Antioxidants or inhibitors | Cell Viability (% of control) | ||
|---|---|---|---|
TNFα | Glutamate | Oligomycin | |
No antioxidant or inhibitor | 0 | 0 | 0 |
Vitamin E, 100 μM | 0 | 100* | 93 ± 4* |
Vitamin C, 100 μM | 0 | 100* | 0 |
BHA, 100 μM | 95 ± 3* | 92 ± 4* | 0 |
BHT, 100 μM | 0 | 45 ± 6* | 0 |
Idebenone, 10 μM | 0 | 97 ± 3* | 0 |
N-Acetylcysteine, 100 μM | 0 | 100* | 0 |
Quercetin, 10 μM | 0 | 96 ± 4* | 0 |
L-NAMEa, 100 μM | 0 | 0 | 0 |
Allopurinol, 100 μM | 0 | 0 | 12 ± 3* |
Desferoxamine, 100 μM | 0 | 91 ± 4* | 0 |
FeTCPP, 50 μM | 0 | 0 | 95 ± 4* |