Indicators | Normal (n= 7) | AFL (n= 6) | HF-NAFL (n= 4) | HL-NAFL (n= 6) | LF§ (n= 5) |
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BW (g) | 270 ± 5¶/457 ± 14§ | 275 ± 3¶ | 418 ± 28§ | 565 ± 29§,* | ND |
AST (U/L) | 154 ± 25 | 148 ± 34c | 164 ± 31 | 181 ± 63 | 199 ± 37* |
ALT (U/L) | 56 ± 15 | 41 ± 13c | 48 ± 17 | 57 ± 22 | 74 ± 19* |
TBIL (mg/dl) | 0.70 ± 0.06 | 0.62 ± 0.09a, b, c | 0.78 ± 0.04 | 0.75 ± 0.05 | 0.84 ± 0.10* |
TG (mg/dl) | 51 ± 16 | 58 ± 10a | 91 ± 14** | 56 ± 11 | 48 ± 14 |
TCHO (mg/dl) | 61 ± 10 | 68 ± 8 | 72 ± 10 | 71 ± 12 | 61 ± 17 |
- BW, body weight; AST, aspartate aminotransferase; ALT, alanine aminotransferase; TBIL, total bilirulin; TG, triglyceride; TCHO, total cholesterol; AFL, alcoholic fatty liver; HF-NAFL, high fructose-induced non-alcoholic fatty liver; HL-NAFL, high lipid-induced non-alcoholic fatty liver; LF, liver fibrosis. Indicators for predicting liver function include GOT, GPT, and bilirubin and for predicting fat cells include triglyceride and cholesterol. Rats were treated before the age of 6 weeks and sacrificed by the ages of ¶10 and §18 weeks. ND, Non-detection. The p value was calculated according to Student's t-test. * p < 0.05 and **p < 0.01 as compared to normal controls. A significant change (p < 0.05) was also determined for AFL rats compared to aHF-NAFL, bHL-NAFL, and cLF rats.