Figure 2
From: siRNA against presenilin 1 (PS1) down regulates amyloid β42 production in IMR-32 cells
Effect of PS1 siRNA on the protein levels of PS1 (a) Immunoblot analysis of PS1 (b) densitometric analysis. 60 μg proteins from IMR 32 cells after PS1 transfection at different concentrations were subjected to westren blot analysis using an anti PS1 antibody (1:250 dilutions). Lane 1: Non siRNA Transfected IMR-32 Cells; Lane 2: Control siRNA; Lane 3: 50 pmoles PS1siRNA; Lane 4: 75 pmoles PS1 siRNA; Lane 5: 100 pmoles PS1 siRNA. Values are mean ± SD (N = 5). *** p < 0.001 significantly different from csiRNA.