Figure 2

Structural representation of FIX (2WPH) native and mutant proteins. a. Structure of FIX native type protein (2WPH) in grey displaying the position of W431 and W453 in sphere shape (green color). b. Superimposed structure of native amino acid tryptophan in sphere shape (green color) with mutant amino acid arginine (red color) at position 412 in ‘S’ chain of 2WPH. c. Superimposed structure of native amino acid tryptophan in sphere shape (green color) with mutant amino acid arginine (red color) at position 453 in ‘S’ chain of 2WPH.