Figure 1From: Association of thymidylate synthase gene 3'-untranslated region polymorphism with sensitivity of non-small cell lung cancer to pemetrexed treatment: TS gene polymorphism and pemetrexed sensitivity in NSCLCDetection of TS gene 3’-UTR 6 bp polymorphism at 1494 bp. Genomic DNA was extracted from blood from patients and subjected to qPCR analysis of the TS gene polymorphism and then to DNA sequencing analysis. A and C, qPCR amplification curves show TS 3’-UTR 1494 bp (−6 bp/-6 bp) and (−6 bp/+6 bp) polymorphisms. B and D, DNA sequencing data on TS 3’-UTR 1494 bp (−6 bp/-6 bp) and (−6 bp/+6 bp).Back to article page