Changes in microRNA expression profile in hippocampus during the acquisition and extinction of cocaine-induced conditioned place preference in rats

Table 1 Differentially expressed miRNAs in hippocampus when rats acquired cocaine CPP

miRNA	SCA	CCA	Ratio of CCA to SCA	Regulation^a
miR-134	0.006139	0.039531	6.44	up
miR-152	0.01482	0.058302	3.93	up
miR-154*	0.015134	0.041161	2.72	up
miR-181c	0.070352	0.119279	1.70	up
miR-181c*	0.092892	0.269775	2.90	up
miR-194	0.032277	0.060462	1.87	up
miR-199a-3p	0.014452	0.075678	5.24	up
miR-26b	1.859555	2.820702	1.52	up
miR-30a*	0.006172	0.040441	6.55	up
miR-344b-2-3p	0.23734	0.396449	1.67	up
miR-34b	0.240389	0.43971	1.83	up
miR-34c	0.16784	0.307303	1.83	up
miR-350	0.149637	0.241594	1.61	up
miR-3597-5p	0.636307	0.988536	1.55	up
miR-369-5p	0.244867	0.368477	1.50	up
miR-409-3p	0.017127	0.054199	3.16	up
miR-423*	0.093672	0.171984	1.84	up
miR-431	0.048806	0.107651	2.21	up
miR-465*	0.021505	0.047859	2.23	up
miR-504	0.015596	0.058488	3.75	up
miR-540*	0.018673	0.051985	2.78	up
miR-542-3p	0.020206	0.059183	2.93	up
miR-665	0.065823	0.102721	1.56	up
miR-674-3p	0.057451	0.117307	2.04	up
miR-770	0.028775	0.047354	1.65	up
miR-872	0.079561	0.134929	1.70	up
miR-874	0.035205	0.058923	1.67	up
miR-877	0.024626	0.061976	2.52	up
miR-878	0.11178	0.181681	1.63	up
miR-133b	0.128301	0.044647	0.35	down
miR-144	0.326406	0.203167	0.62	down
miR-191	5.170566	2.72656	0.53	down
miR-224*	0.245938	0.006648	0.03	down
miR-451	1.690767	1.024982	0.61	down

Data are expressed as normalized median. SCA, repeated saline-exposed rats with CPP procedure; CCA, repeated cocaine-exposed rats that acquired cocaine CPP.
a, p < 0.05 vs. SCA, and fold change > = 1.5.

ISSN: 1423-0127