Figure 5From: Mutations in the non-structural protein region contribute to intra-genotypic evolution of enterovirus 71The frequency of amino acid substitutions in polyprotein of China strains from 1998 to 2012. Amino acid sequences were aligned by Clustal X program and the gene signature was displayed using the Phylo-mLogo program. The frequency of amino acid sequences relative to the total number of sequences in each indicated period are shown.Back to article page