Table 2 Urinary biochemistry profile

Bodyweight (g)

0

140.40 ± 1.24

130.70 ± 3.18

131.01 ± 3.42

133.57 ± 2.66

133.38 ± 2.27

7

173.49 ± 2.34

134.37 ± 2.01^a*

145.59 ± 2.82^a*

142.27 ± 3.70^a*

140.42 ± 2.10^a*

14

218.31 ± 3.32

151.16 ± 2.64

160.88 ± 2.69

164.90 ± 3.38

150.82 ± 3.01

21

240.39 ± 2.75

171.17 ± 3.04

180.17 ± 3.25

190.76 ± 3.39

171.42 ± 3.35

28

261.11 ± 2.87

195.13 ± 3.70^a*

191.80 ± 2.06^a*

220.14 ± 2.68^{a* b*c*}

201.73 ± 2.51^{a* b*c*}

Urine pH

0

7.07 ± 0.11

6.83 ± 0.26

6.84 ± 0.19

6.74 ± 0.25

6.54 ± 0.15

7

7.13 ± 0.16

7.08 ± 0.18

6.94 ± 0.20

7.11 ± 0.18

7.29 ± 0.12

14

7.10 ± 0.22

6.94 ± 0.30

6.94 ± 0.24

6.97 ± 0.20

7.02 ± 0.15

21

7.21 ± 0.15

6.44 ± 0.19^a*

6.55 ± 0.12^a*

6.86 ± 0.21^b*c*

6.94 ± 0.16

28

7.25 ± 0.11

6.09 ± 0.07^a*

6.16 ± 0.08^a*

6.90 ± 0.17^{a* b*c*}

6.79 ± 0.13^{a* b*c*}

Uric acid (mg/24 h)

0

0.05 ± 0.01

0.09 ± 0.01

0.06 ± 0.01

0.05 ± 0.01

0.05 ± 0.01

7

0.12 ± 0.01

0.14 ± 0.01

0.16 ± 0.01

0.07 ± 0.01

0.12 ± 0.04

14

0.11 ± 0.02

0.18 ± 0.01^a*

0.19 ± 0.01^a*

0.09 ± 0.01^b*c*

0.14 ± 0.01^b*c*

21

0.15 ± 0.02

0.21 ± 0.02^a*

0.25 ± 0.03^a*

0.11 ± 0.03^b*c*

0.15 ± 0.01^b*c*

28

0.17 ± 0.02

0.46 ± 0.02^a*

0.39 ± 0.03^a*

0.12 ± 0.01^b*c*

0.18 ± 0.02^b*c*

Creatinine (mg/24 h)

0

1.33 ± 0.08

1.39 ± 0.18

1.23 ± 0.15

1.11 ± 0.11

1.16 ± 0.08

7

1.04 ± 0.06

1.50 ± 0.16^a*

1.69 ± 0.26^a*

1.41 ± 0.11^a*

1.73 ± 0.10^a*

14

1.64 ± 0.24

1.73 ± 0.13^a*

2.82 ± 0.29^a*

1.61 ± 0.18^c*

1.95 ± 0.18^c*

21

1.51 ± 0.31

2.71 ± 0.19^a*

3.19 ± 0.22^a*

2.07 ± 0.09^a*b*c*

2.30 ± 0.16^a*b*c*

28

1.77 ± 0.23

3.69 ± 0.30^a*

3.52 ± 0.19^a*

2.52 ± 0.14^a*b*c*

3.07 ± 0.61^a*c*