Table 2 Unconditional logistic regression analysis of genotype polymorphisms of FA genes and multiple risk factors for lung adenocarcinoma development

   AA vs. AG,GG

2.06

1.13–3.72

  FANCD1(rs9634672)

   TT vs. GT,GG

2.24

1.31–3.85

  FANCL(rs12470316)

   TT vs. CT, CC

1.78

1.02–3.13

Cigarette smoking

   Yes vs. No

2.29

1.80–4.46

Passive smoking

   Yes vs. No

2.83

1.79–4.46

Female lung cancer patients

FA gene

  FANCC(rs4744451)

   GG vs. GT,TT

1.67

1.01–2.75

  FANCD1(rs9534275)

   AA vs. AC,CC

1.62

1.20–2.32

  FANCJ/BRIP1/BACH1(rs16945628)

   CC vs. CT, TT

1.44

1.02–2.01

Passive smoking

   Yes vs. No

2.14

1.50–3.03