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Table 1 Percentage of morphant phenotypes during knockdown of YY1a by YY1-morpholines

From: Knockdown of zebrafish YY1a can downregulate the phosphatidylserine (PS) receptor expression, leading to induce the abnormal brain and heart development

Phenotypea

Control-MO

YY1-MO

 

50 ng

12.5 ng

25 ng

50 ng

Number of embryos

126

174

178

174

Normal type

92.0 %

40.0 %

5.6 %

1.3 %

Weakly defective

8.0 %

41.7 %

10.2 %

3.6 %

Severely defective

 

8.0 %

20.2 %

7.3 %

Death type

 

10.3 %

64.0 %

87.8 %

  1. aAll embryos were examined at 2 dpf
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Journal of Biomedical Science

ISSN: 1423-0127