Variables | OS | DFS | ||
---|---|---|---|---|
Hazard ratio (95 % CI) | P | Hazard ratio (95 % CI) | P | |
Sex(male vs female) | 1.126 (0.525–2.416) | 0.76 | 1.483 (0.844–2.608) | 0.171 |
Age,y(≥53 vs. < 53) | 1.609 (0.902–2.874) | 0.107 | 0.802 (0.361–1.781) | 0.588 |
Preoperative AFP, ng/ml (>20 vs. ≤ 20) | 1.320 (0.721–2.415) | 0.369 | 1.390 (0.778–2.485) | 0.266 |
HBsAg (negative vs.positive) | 1.175 (0.598–2.311) | 0.639 | 1.040 (0.563–1.925) | 0.899 |
Liver cirrhosis (yes vs. no) | 3.303 (1.290–8.455) | 0.013 | 2.878 (1.121–7.385) | 0.028 |
Vascular invasion (yes vs. no) | 1.976 (1.004–3.891) | 0.049 | 0.922 (0.523–1.625) | 0.78 |
Tumor size, cm (>5 vs. ≤ 5) | 1.107 (0.609–2.014) | 0.738 | 0.818 (0.468–1.429) | 0.48 |
Tumor number (multiple vs.single) | 1.718 (0.886–3.330) | 0.109 | 1.265 (0.646–2.475) | 0.493 |
Tumor differentiation (I-II vs.III-IV) | 1.215 (0.566–2.608) | 0.618 | 0.971 (0.472–1.999) | 0.937 |
TNM stage (III vs.I-II) | 2.253 (1.209–4.199) | 0.011 | 2.137 (1.177–3.880) | 0.013 |
BCLC stage (C vs. A/B) | 1.976 (1.004–3.891) | 0.049 | 0.922 (0.523–1.625) | 0.78 |
Intratumoral GABAARγ2 (high vs.low) | 0.372 (0.203–0.683) | 0.001 | 0.419 (0.232–0.755) | 0.004 |
Peritumoral GABAARγ2 (high vs.low) | 1.302 (0.719–2.355) | 0.384 | 1.503 (0.850–2.657) | 0.161 |