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Fig. 5 | Journal of Biomedical Science

Fig. 5

From: Establishment and evaluation of module-based immune-associated gene signature to predict overall survival in patients of colon adenocarcinoma

Fig. 5

Risk score is correlating with immunosuppressive tumor microenvironment in COAD patients. A Hierarchical cluster and heatmap of the enrichment scores of the various gene sets related to immune functions on the COAD patients (n = 334). B Boxplot indicating the sum of the immune enrichment scores (SIES) in cluster1 and clsuter2. p-value is calculated by unpaired two tailed t test. C Boxplot indicating the risk score of COAD patients in cluster1 and cluster 2 (n = 313). p-value is calculated by unpaired two tailed t test. D Boxplot indicating the SIES in patients of low- and high- risk (according to the risk score stratification). p-value is calculated by unpaired two tailed t test. E Dot heatmap of the Pearson correlation between risk score and enrichment score of the various gene sets related to immune functions. Dot size indicate the correlation extent

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Journal of Biomedical Science

ISSN: 1423-0127