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Table 2 Plasma and urine electrolyte levels in Rrbp1-WT and Rrbp1-KO mice

From: ER ribosomal-binding protein 1 regulates blood pressure and potassium homeostasis by modulating intracellular renin trafficking

Genotype (n)

Rrbp1-WT (n = 21)

Rrbp1-KO (n = 16)

Blood

[K+], mmol/L

6.28 ± 0.11

6.77 ± 0.14 †

[Na+], mmol/L

149.6 ± 0.65

149.6 ± 0.71

[Cl−], mmol/L

113.9 ± 0.59

113.9 ± 0.59

Urine

TTKG

9.5 ± 0.1

9.1 ± 0.2

FEK+

16.4 ± 1.0

11.5 ± 0.8 ‡

FENa+

0.32 ± 0.02

0.24 ± 0.02 *

FECl−

0.70 ± 0.04

0.56 ± 0.05 *

  1. TTKG, transtubular potassium gradient; FE, fractional excretion
  2. *P < 0.05, †P < 0.01, ‡P < 0.001 Rrbp1-KO (knock-out) vs. Rrbp1-WT (wild-type)
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Journal of Biomedical Science

ISSN: 1423-0127