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Fig. 6 | Journal of Biomedical Science

Fig. 6

From: Downregulation of the RNA-binding protein PUM2 facilitates MSC-driven bone regeneration and prevents OVX-induced bone loss

Fig. 6

Graphical abstract of PUM2-mediated osteogenesis in MSCs. A PUM2 inhibits translation of DLX5 by interacting with the 3’-UTR of DLX5 mRNA. B MSCs with PUM2 knockdown showed potential as cell therapy for the regeneration of damaged bone tissue. C AAV9 loaded with siRNA targeting Pum2 showed potential as a gene therapy that can alleviate osteoporosis symptoms through systemic injection

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Journal of Biomedical Science

ISSN: 1423-0127