Fig. 8

The level of phospho-HDAC2, HDAC2, Sin3A, and MeCP2 and acetylation of H3 in the lungs of mice with OVA-induced airway fibrosis. A The level of phospho-HDAC2, HDAC2, Sin3A, MeCP2, and acetylation of H3 in the lungs from PBS-treated or OVA-treated mice were evaluated through Western blotting. B–F Statistical analysis of protein levels. Horizontal lines indicate mean values, and each dot represents an individual mouse (n = 10). *p < 0.05 versus PBS group. G Paraffin sections of lung tissue from the PBS- or OVA-treated mice were stained for phospho-HDAC2 (purple), HDAC2 (green), Sin3A (red), and nuclei (blue). Bar, 50 μm