The RNA-binding protein KSRP aggravates malignant progression of clear cell renal cell carcinoma through transcriptional inhibition and post-transcriptional destabilization of the NEDD4L ubiquitin ligase

Table 1 Correlation of clinical parameters and KH-type splicing regulatory protein (KSRP) in clear cell renal cell carcinoma (ccRCC)

Clinicopathological feature	N	KSRP expression, n (%)
	534	Low	High	p value
	534	369 (69.1)	165 (30.9)	p value
T stage
T1 + T2	343	253	90	*0.002*
T3 + T4	191	116	75
N stage
N0	240	163	77	0.654
N1	16	10	6
M stage
M0	422	297	125	0.056
M1	79	47	32
Stage
I + II	325	238	87	*0.011*
III + IV	207	130	77
Recurrence
No	414	299	115	*0.004*
Yes	109	63	46

The significance of the statistical analysis is indicated by the bold and italic values of the p-value

ISSN: 1423-0127