Fig. 1

Selection of specific scFv phages against the conserved U1 (SLLTEVETPI) epitope M2e of influenza. A Schematic diagram of M2 protein of the influenza virus and U1 N-terminal conserved sequence highlighted in red. B Sequence alignment of M2e of M2 protein of different strains of the influenza viruses. C Percentage variations of M2e ectodomain at each residue. All strain sequences (64,936) were extracted from Influenza Research Database, and percentage mutations for each residue were calculated (http://www.fludb.org). (Y axis: Number of residues or amino acid residues in the sequence of M2e domain and X axis: Percentage of mutation per residue)