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Table 2 Resistance genotypes in association with phenotypic characteristics

From: Various arrangements of mobile genetic elements among CC147 subpopulations of Klebsiella pneumoniae harboring blaNDM-1: a comparative genomic analysis of carbapenem resistant strains

Resistant phenotype

gyrA/parC n (%)a

qnrS1

aac(6)-Ib-cr

aadA1

aadA5

armA

aac3IIa

aph3Ib/aph6Id

Ciprofloxacin (n = 41)

27 (65.9%)

25 (61%)

19 (46.3%)

ND

ND

ND

ND

ND

P values

0.001

 < 0.001

0.002

–

–

–

–

–

Levofloxacin (n = 36)

27 (77.1%)

23 (65.7%)

19 (54.3%)

ND

ND

ND

ND

ND

P values

< 0.001

< 0.001

< 0.001

–

–

–

–

–

Amikacin (n = 12)

ND

ND

9 (75%)

7 (58.3%)

5 (41.7%)

7 (58.3%)

8 (66.7%)

3 (25%)

P value

–

–

0.002

< 0.001

0.9

< 0.001

0.3

0.5

Gentamicin (n = 35)

ND

ND

18 (51.4%)

10 (28.6%)

18 (51.4%)

8 (22.9%)

27 (77.1%)

10 (28.6%)

P value

–

–

0.001

0.01

0.001

0.04

 < 0.001

0.2

Tobramycin (n = 34)

ND

ND

19 (55.9%)

10 (29.4%)

19 (55.9%)

8 (23.5%)

27 (79.4%)

8 (23.5%)

P value

–

–

< 0.001

0.009

< 0.001

0.02

< 0.001

0.03

  1. a: n (%) represents the positivity within resistance rates against each antibiotic
  2. ND: not determined
  3. Underlined: represents negative association
  4. Bolded: represents the positive association