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Fig. 11 | Journal of Biomedical Science

Fig. 11

From: Long noncoding RNA SNHG16 regulates TLR4-mediated autophagy and NETosis formation in alveolar hemorrhage associated with systemic lupus erythematosus

Fig. 11

AH in pristane-injected mice receiving intra-pulmonary sh-SNHG16 delivery on different days. Hemorrhagic frequencies on day 14 in pristane-injected mice receiving a day − 1 prophylactic, d day 4 early therapeutic and g day 8 late therapeutic intra-pulmonary delivery of sh-luciferase or sh-SNHG16. RBC numbers, Hb levels and Hct on day 14 in mice receiving b day − 1 prophylactic, e day 4 early therapeutic and h day 8 late therapeutic intra-pulmonary delivery of sh-luciferase or sh-SNHG16. Pulmonary SNHG16 levels on day 14 in mice receiving c day − 1 prophylactic, f day 4 early therapeutic and i day 8 late therapeutic intra-pulmonary delivery of sh-luciferase or sh-SNHG16. Values are mean ± SD. Horizontal lines are mean values. Mouse numbers per group, 16 in a, b, d, e, g, h, 8 in c, f, i. All results in figure were representative of 2 independent experiments with similar findings. *p < 0.05, **p < 0.01, ***p < 0.001

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Journal of Biomedical Science

ISSN: 1423-0127