Fig. 2

Up-regulated cell death processes and pulmonary expression of SNHG16, TLR4 and TRAF6 in SLE-associated AH lung tissues. a Quantification of cell numbers with positive TUNEL, colocalized CitH3 and DNAs, and cytoplasmic LC3 in lung tissues from PTX controls and AH patients from SLE, IgAV and AAV. Expression levels of b SNHG16, c TLR4, d TRAF6, e miR-146a and f NEAT1 in lung tissues from PTX controls and AH patients from SLE, IgAV and AAV. Expression levels of g p53, h Bax, i HGMB1, j PAD4, k LC3, l Beclin-1, m mTOR, n p62, o IL-6, p IL-8, q IFN-α and r MX-1 in lung tissues from PTX controls and SLE-AH patients. Lung sample numbers, n = 5 for PTX, n = 3 for SLE, n = 1 for IgAV, n = 1 for AAV. Values are mean ± SD. Horizontal lines are mean values. *p < 0.05