Fig. 1
From: LncRNA SLCO4A1-AS1 suppresses lung cancer progression by sequestering the TOX4-NTSR1 signaling axis
SLCO4A1-AS1 is significantly downregulated in highly metastatic lung cancer cells and NSCLC patients. A Heat map of lncRNA expression in PC9 and PC9/gef cells from the GEO database (GSE60189). B The differential expression fold change of lncRNAs is listed from the database (left) and validated by RT-qPCR (right). C SLCO4A1-AS1 expression in LUAD, LUSC, BRCA, and LIHC tissues from Gene Expression Profiling Interactive Analysis (GEPIA) database. D RNA-seq data revealed SLCO4A1-AS1 transcript expression in 90 pairs of lung tumors and corresponding adjacent normal tissues in Taiwan Lung Adenocarcinoma Patient Cohort (dbGaP Study Accession: phs001954.v1.p1). The data was analyzed using a paired Wilcoxon test (p = 0.038). E The correlation between SLCO4A1-AS1 expression and overall survival (log rank test, p = 0.033), and first progression (log rank test, p = 0.034) of lung cancer patients from GSE31210 in Kaplan–Meier plotter database website. LUAD lung adenocarcinoma, LUSC lung squamous cell carcinoma, BRCA breast invasive carcinoma, LIHC liver hepatocellular carcinoma