Fig. 3

Correlation of ARID1A, DUSP4, and MAPKs expression levels in vivo and in silico: a Representative photomicrographs of MAPKs (p-p38, p-JNK, and p-ERK) immunoreactivity in iAD and iPD mice in the presence or absence of doxycycline-induced gene deletion. b H-score semi-quantification of MAPK immunoreactivity in iAD and iPD mice. c, d, g Spearman’s correlation between ARID1A and MAPKs in the three indicated datasets. e, f Spearman’s correlation between DUSP4 and MAPKs in the two indicated datasets. In c–g, the red bar indicates the p-value (p < 0.05 is considered significant). c–f Data were retrieved from the TCPA website (https://tcpaportal.org/tcpa/) g Data were retrieved from TCGA through cBioPortal (https://www.cbioportal.org/)