T cell expressions of aberrant gene signatures and Co-inhibitory receptors (Co-IRs) as predictors of renal damage and lupus disease activity

Table 2 Expression distribution of CD8 T cells for CD161, GZMB, and GZMK in SLE, ESRD and normal

Markers	Mean ± SD (Number)		P Value	Mean ± SD (Number)		P Value
Markers	Normal	ESRD-SLE	P Value	Normal	SLE	P Value
45RA-197–8 + GZMB + in CD8	9.320 ± 1.169 (25)	19.20 ± 4.748 (5)	0.0057	9.320 ± 1.169 (25)	26.32 ± 2.474 (38)	< 0.0001
45RA-197–8 + GZMK + in CD8	19.96 ± 1.685 (25)	20.20 ± 5.257 (5)	0.9569	19.96 ± 1.685 (25)	19.18 ± 1.834 (38)	0.7702
45RA-8 + 103–161-GZMK + in CD8	4.207 ± 0.6274 (25)	11.29 ± 4.934 (5)	0.0082	4.207 ± 0.6274 (25)	6.989 ± 1.461 (38)	0.1432
45RA-8 + 103–161-GZMK + GZMB + in CD8	1.874 ± 0.2710 (25)	7.846 ± 4.233 (5)	0.0033	1.874 ± 0.2710 (25)	5.295 ± 1.282 (38)	0.0365
45RA-8 + 103–161 + GZMK + in CD8	6.067 ± 1.066 (25)	2.070 ± 1.182 (5)	0.1164	6.067 ± 1.066 (25)	1.234 ± 0.2120 (38)	< 0.0001

ISSN: 1423-0127