Table 3 CD4 and CD8 T cell expression of cell single activation and Co-IRs in SLE and normal

CD4 + CD279 + 

8.027 ± 0.7983 (91)

3.93 ± 0.7035 (27)

0.008

CD4 + TIM3 + 

4.869 ± 0.5852 (91)

4.015 ± 0.9389 (26)

0.4801

CD4 + CTLA4 + 

0.2584 ± 0.06174 (89)

0.08889 ± 0.0209 (27)

0.1363

CD4 + LAG3 + 

1.013 ± 0.1755 (91)

0.84 ± 0.1783 (25)

0.6201

CD4 + CD127 + 

33.85 ± 2.343 (90)

44.59 ± 5.149 (27)

0.0382

CD4 + TIGIT + 

25.67 ± 1.119 (90)

20.13 ± 0.8377 (26)

0.0109

CD8 + CD279 + 

7.718 ± 0.8665 (91)

4.896 ± 0.9672 (27)

0.0955

CD8 + TIM3 + 

12.56 ± 0.9711 (91)

9.826 ± 1.19 (27)

0.1534

CD8 + CTLA4 + 

0.2225 ± 0.03828 (89)

0.163 ± 0.03626 (27)

0.4132

CD8 + LAG3 + 

0.5511 ± 0.1479 (90)

0.1963 ± 0.05324 (27)

0.1954

CD8 + CD127 + 

22.46 ± 1.752 (90)

40.86 ± 4.19 (27)

 < 0.0001

CD8 + TIGIT + 

35.06 ± 1.65 (90)

25.81 ± 1.774 (27)

0.0042

CD8 + CD160 + 

33.69 ± 1.574 (89)

29.04 ± 1.988 (27)

0.1322

CD8 + CD244 + 

1.634 ± 0.358 (88)

1.726 ± 0.4429 (27)

0.8947

CD8 + HLA-DR + 

46.74 ± 2.319 (51)

18.6 ± 1.909 (17)

 < 0.0001

CD8 + CD38 + 

25.92 ± 1.962 (51)

22.97 ± 2.123 (17)

0.4186

CD3 + CD160 + 

16.92 ± 1.199 (91)

10.93 ± 1.137 (27)

0.0101

CD3 + CD244 + 

5.79 ± 1.11 (91)

7.477 ± 2.673 (26)

0.5041

CD3 + CD279 + 

6.824 ± 0.6774 (91)

3.978 ± 0.7626 (27)

0.0323

CD3 + TIGIT + 

32.06 ± 1.643 (91)

28 ± 2.888 (27)

0.235

CD3 + NKG2C + 

8.953 ± 1.342 (91)

9 ± 2.623 (26)

0.9869