Table 4 CD4 and CD8 T cell expression of cell double activation and Co-IRs in SLE and normal

CD4 + CD279 + TIM3 + 

0.6607 ± 0.09546 (89)

0.3667 ± 0.0859 (27)

0.1052

CD4 + CTLA4 + LAG3 + 

0.1733 ± 0.04774 (90)

0.07037 ± 0.02123 (27)

0.2454

CD4 + CD127 + TIGIT + 

4.133 ± 0.3952 (90)

5.041 ± 0.6587 (27)

0.2632

CD8 + CD279 + TIM3 + 

0.5922 ± 0.09517 (90)

0.08077 ± 0.01666 (26)

0.0048

CD8 + CTLA4 + LAG3 + 

0.01429 ± 0.004835 (91)

0.007407 ± 0.005136 (27)

0.4621

CD8 + CD127 + TIGIT + 

2.266 ± 0.2667 (90)

2.426 ± 0.4004 (27)

0.7647

CD8 + CD160 + CD244 + 

0.5455 ± 0.1769 (88)

0.8556 ± 0.3153 (27)

0.3961

CD8 + HLA-DR + CD127 + 

1.923 ± 0.3112 (53)

1.716 ± 0.3932 (19)

0.7185

CD8 + HLA-DR + CD38 + 

13.75 ± 1.162 (87)

4.519 ± 0.8416 (27)

 < 0.0001

CD3 + CD160 + CD244 + 

0.4652 ± 0.06847 (89)

0.2423 ± 0.06255 (26)

0.0927

CD3 + CD279 + TIGIT + 

4.089 ± 0.4359 (91)

2.804 ± 0.5352 (27)

0.1346