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Figure 4 | Journal of Biomedical Science

Figure 4

From: Molecular events associated with epithelial to mesenchymal transition of nasopharyngeal carcinoma cells in the absence of Epstein-Barr virus genome

Figure 4

Morphological changes of NPC-BM1 cells after separation of invasive from non-invasive cells. Cells were plated in low density and photographed after 36 h using light microscopy (× 200 magnification). Panel A, parental cells (NPC-BM1); B, cells (NPC-BM18) after the first round of selection; C, cells (NPC-BM29) after the second round of selection. NPC BM1 exhibited typical well-attached polygonal epithelial cell morphology with few round and packed appearance cells (arrows) representing EMT morphology. These EMT cells increased in NPC-BM18 and NPC-BM29. The epithelial to mesenchymal transition (EMT) is characterized by the loss of epithelial characteristics and the gain of mesenchymal attributes in epithelial cells. Panels (A) and (C) are the higher power view of panels A and C. Magnification 450 ×.

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Journal of Biomedical Science

ISSN: 1423-0127