Figure 4

Differences in two types of calcium currents recorded from healthy and myopathic LA-PV cardiomyocytes. A and B: selected membrane currents elicited by depolarizing clamps to various voltages from the holding potentials (Vh) of -90 mV (I) and -50 mV (II, ICa,L). Horizontal arrows near left margin indicate zero current. The difference current (I-II, ICa,T) was obtained from the subtraction of current elicited from -90 mV and -50 mV, respectively. C: Mean current densities of peak ICa,L and ICa,T from 10 myopathic and 12 healthy LA-PV myocytes. *P < 0.05 by group comparisons.