Figure 6

Delayed outward K⁺ current (I _K ) activated on depolarization in LA-PV healthy (panel A) and myopathic myocytes (panel B). Clamp protocol is shown at the top of panel B. I_K was measured near the end of the 1 s depolarizing pulses. Downward solid triangle indicated I_K recorded at test potential of +60 mV. In contrast, open triangle indicated I_TO in the same myocytes. Panel C shows the mean current-voltage relations of I_K in 45 healthy (closed circles) and 34 myopathic myocytes (open circles).