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Table 1 Electrophysiological properties of healthy and myopathic LA-PV cardiomyocytes isolated from 18 healthy and 17 myopathic Syrian hamsters

From: Reduced Ca2+ transport across sarcolemma but enhanced spontaneous activity in cardiomyocytes isolated from left atrium-pulmonary veins tissue of myopathic hamster

  Myopathic Healthy
Cm(pF) 47 ± 3*(67) 33 ± 2 (83)
APA (mV) 81 ± 3 (29) 87 ± 2 (42)
Phase-0 (mV/ms) 14.1 ± 2.1*(25) 24.2 ± 1.9(34)
MDP (-mV) 60 ± 1 (29) 57 ± 1 (42)
APD20 (msec) 21 ± 3 (29) 26 ± 3 (42)
APD50 (msec) 40 ± 5* (29) 64 ± 9 (42)
APD90 (msec) 77 ± 8* (29) 109 ± 11 (42)
  1. Cm, membrane capacitance of myocyte. For action potential parameters: Steady-state (driven at 1 Hz) values are given in mean ± S.E.M. APA, action potential amplitude. Phase-0 (mV/ms), maximum dV/dt of phase-0 depolarization. MDP, maximum diastolic potential; APD20, APD50, and APD90: action potential duration at 20%, 50% and 90%, respectively, of repolarization levels. Number in parenthesis indicates number of myocytes. *P < 0.05 by group comparisons between healthy and myopathic hamsters.