Journal of Biomedical Science

Table 2 The gastric cytokine expressions on the 2^nd week of young and adult mice with persistent H. pylori colonization and naïve control mice.

From: Persistent H. pylori colonization in early acquisition age of mice related with higher gastric sialylated Lewis x, IL-10, but lower interferon-γ expressions

		Young mice			Adult mice
Parameter (%)		Colonized (n = 8)	Control (n = 10)	P value	Colonized (n = 10)	Control (n = 10)	P Value
IL-6*	Matrix	75	20	0.05	70	30	NS
	Lymphocyte	50	10	NS	60	70	NS
	Fibrocyte	75	0	0.002	80	50	NS
	Neutrophil	37.5	20	NS	20	70	0.07
TNF-α *	Matrix	87.5	70	NS	80	90	NS
	Lymphocyte	62.5	40	NS	90	90	NS
	Fibrocyte	87.5	40	0.07	100	90	NS
	Neutrophil	12.5	10	NS	30	40	NS
IL-1β	Epithelium ≥ 2	100	70	NS	100	90	NS
	Matrix	^a25	0	NS	100	80	NS
	Lymphocyte	25	20	NS	30	0	NS
	Fibrocyte	^a25	60	NS	100	100	NS
IFN-γ	Epithelium ≥ 2	0	30	NS	10	0	NS
	Matrix	0	100	< 0.001	40	20	NS
	Lymphocyte	0	0	NS	10	30	NS
	Fibrocyte	12.5	10	NS	30	90	0.02
	Neutrophil	0	0	NS	10	20	NS
IL-10*	Matrix	^a25	60	NS	100	80	NS
	Lymphocyte	25	20	NS	60	60	NS
	Fibrocyte	^a37.5	50	NS	100	80	NS
	Neutrophil	12.5	0	NS	10	20	NS

CIS: chronic inflammatory score; AIS: acute inflammatory score. *: colonized means mice infected with H. pylori with successful colonization (positive urea test and histology) on sacrifice. ^a: P value < 0.01; ^b: P value ≤ 0.05 between the young and adult colonized mice. NS: no significance. *indicated on this parameter, the epithelium is rather weak for such cytokine on immunohistochemistry staining.

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ISSN: 1423-0127

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