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Table 2 The gastric cytokine expressions on the 2nd week of young and adult mice with persistent H. pylori colonization and naïve control mice.

From: Persistent H. pylori colonization in early acquisition age of mice related with higher gastric sialylated Lewis x, IL-10, but lower interferon-γ expressions

   Young mice Adult mice
Parameter (%) Colonized
(n = 8)
Control
(n = 10)
P value Colonized
(n = 10)
Control
(n = 10)
P Value
IL-6* Matrix 75 20 0.05 70 30 NS
  Lymphocyte 50 10 NS 60 70 NS
  Fibrocyte 75 0 0.002 80 50 NS
  Neutrophil 37.5 20 NS 20 70 0.07
TNF-α * Matrix 87.5 70 NS 80 90 NS
  Lymphocyte 62.5 40 NS 90 90 NS
  Fibrocyte 87.5 40 0.07 100 90 NS
  Neutrophil 12.5 10 NS 30 40 NS
IL-1β Epithelium ≥ 2 100 70 NS 100 90 NS
  Matrix a25 0 NS 100 80 NS
  Lymphocyte 25 20 NS 30 0 NS
  Fibrocyte a25 60 NS 100 100 NS
IFN-γ Epithelium ≥ 2 0 30 NS 10 0 NS
  Matrix 0 100 < 0.001 40 20 NS
  Lymphocyte 0 0 NS 10 30 NS
  Fibrocyte 12.5 10 NS 30 90 0.02
  Neutrophil 0 0 NS 10 20 NS
IL-10* Matrix a25 60 NS 100 80 NS
  Lymphocyte 25 20 NS 60 60 NS
  Fibrocyte a37.5 50 NS 100 80 NS
  Neutrophil 12.5 0 NS 10 20 NS
  1. CIS: chronic inflammatory score; AIS: acute inflammatory score. *: colonized means mice infected with H. pylori with successful colonization (positive urea test and histology) on sacrifice. a: P value < 0.01; b: P value ≤ 0.05 between the young and adult colonized mice. NS: no significance. *indicated on this parameter, the epithelium is rather weak for such cytokine on immunohistochemistry staining.